Tuesday, March 17, 2020

buy custom Anorexia Nervosa essay

buy custom Anorexia Nervosa essay Eating Disorder An eating disorder is a type of illness that is characterized by eating behaviors that deviate from the normal eating habits and is usually a response to a psychological or emotional need of self criticism and negative thoughts of oneself. In trying to satisfy these needs, a person develops certain rituals about food, weight, and body shape leading to indulgence in over eating or refusing to eat by ignoring normal body signals for example not eating even when hungry or consuming excess food even when the person is satisfied. Abnormal eating patterns which include anorexia nervosa, bulimia nervosa and binge eating are the three major types of disorders. Anorexia Nervosa Anorexia nervosa is a type of eating isorder where a person has an extreme weight phobia and has an obsession to remain being thin always. Due to this fear, people with anorexia strive to keep their body weight to the low by self starvation or refusing to eat, self-induced vomiting, fasting or by doing excessive exercises and abuse of diet aids. Although there are few cases affecting men, this disorder is usually common with young women starting usually at the adolescence stage or early childhood. Causes of anorexia are not clearly known although certain mixed causes involving psychological factors, social factors, age, stress levels, family and genetic influence are believed to take role. Some of the symptoms of anorexia include intense weight phobia, desire to lose weight despite being thin, constant awareness of their weight, excessive exercises and keeping strict routines of them, certain food choices like salads and for women, lack menstrual periods. Some of the effects of anorexia may include malnutrition, emaciation, hair loss, low blood pressure, organ failures, bone thinning, brain damage, infertility and even death. Treatment of anorexia has not been uniquely identified although many of the forms of treatment include medical supervision, psychotherapy and nutrition therapy. An attempt to restore weight to a healthy and normal size is the key component to any form of treatment but some extreme cases of weight loss may require hospitalization. The use of some medicines such as antidepressants, mood stabilizers and antipsychotics has also been thought to treat anorexia. A better form of treatment involving a combination of supervised medical attention and supportive psychotherapy is also currently being proposed and is thought to be effective than therapy alone. Buy custom Anorexia Nervosa essay

Saturday, February 29, 2020

Analysis of Linear DNA Genomes Separation in Gel Electrophoresis

Agarose gel electrophoresis has been widely used as a form of separating DNA genomes in varying sizes from 100 kp upto 25 kb. Isolation of Agarose gel is obtained from the genera Gelidium and Gracilaria.in the gelato process, the polymers of agarose often form an association of none covalent which form networks of pore sizes which determine the molecular ability of sieving properties. Use of gel electrophoresis is beneficial in separation of DNA genomes. Electrophoresis process is key in separating the different nucleic acids using various sizes and charges depending on the contents of the solution. In this experiment, lab analysis of gel was used to put gel solutions in charged nucleic acids for separation purposes. At this point the larger DNA and RNA have a hard time in separating thus allowing time for separation of the genomes based on the sizes. The rate of separation of the DNA molecule in the experiment was determined by the rate at which the sizes of the DNA, the concentration of the gel, DNA Conformation present, voltage degree applied, ehidium bromide solution introduced, type of agarose and the buffer being utilized in electrophoresis. After the process of separation, DNA molecules will be able to be visualized in the UV light using staining process to identify the different genomes. Thus in essence DAN electrophoresis defines the process by which the DNA migrates in the supporting medium. Most of electrophoresis is carried in agarose gels in narrow polymers of gels using pores of different sizes, this sieving provides a means by which the pores gives an opportunity for the DNA molecules to go through the pores at different sizes thus being separated using molecular weights. Thus this laboratory report uses agarose Gels while staining with ethidium bromide   to assess the separation process of the different DNA genomes. Thus it seeks to investigate the DNA genome separation to assess the different nucleic acids by their respective sizes. Refer to the Lab Manual 5 for in-depth methodology and procedure. Diagrammatic presentation of gel DNA Table 1; Showing gel electrophoresis picture Table 2; Showing curve presentation of the base pairs against distance travelled Table 3; Showing table figure for the curve Table 4; Showing how to calculate base pairs Example suppose we have a base pair having travelled 0.3 cm, then draw a line as illustrated above and take the readings on the corresponding logbp and take the anti log, which you get the base pair size. Table 5; Showing the sizes of pUC19 and their insert sizes Agarose gel electrophoresis has been utilised as a common method for separation of proteins, (Kryndushkin et al., 2003). The basic forms of nucleic acids can be separated through the aid of electrification process whereby charged molecules move to the anode side. This migration as depicted in the experiment ensures that molecules which have lower molecular weight are able to move faster, (Sambrook & Russel 2001). The process of electrophoresis is a crucial step in ensuring purification process of the desired DNA bands. In this experiment the usage of ethidium bromide is essential in visualizing the staining of the transcend DNA molecules. In this task, the Agarose gel electrophoresis plays a key role in ensuring the characteristics of DNA are obtained without any alterations. This experiment has yielded results which have enabled determination of DNA fragments sizes through digestion by restriction enzymes. The visualization has been effected with the use of ethidium bromide which is a common agent in nucleic acid purification process. The Agarose gel concentration on this task entailed the separation of the gel using agarose gel concentration of 0.2%w/v having bands from 0.1-1 kb. The distance travelled by DNA molecules in electrophoresis is directly proportional to the size of the DNA itself. The agarose gel is beneficial in ensuring that there are movements based on their sizes. With the various differences between the various rates of the DNA molecules in the gel solution, they are separated based on the size of the bases. The relationship built between the varied sizes of the DNA genome. The sieving of DNA is done through the size which it bears, (Southern, 1975). The length of DNA strands often vary from 50 base pairs to upto million s base pairs which agarose gel electrophoresis can be effective in separating them , the migration and distance travelled is linked on the concentration of the agarose used to prepare the gel. Concentrations having lower concentration are able to travel faster in the distance travelled and vice versa. In this study agarose gel of 2% has been used which was effective in separating the DNA at range of 0.1-1 kb, the low percentile gels often signify gels which are weak. Double stranded DNA moves faster as the molecules travels; its speed is inversely proportional to the logarithm of base pairs. This linked and established relationships depends on the strength of the of gel composition. The distance travelled by the digested genome signifies that there is action of restriction enzymes which shows that there restrictions which have taken place, thus distinguishing the variability linked to genetics and enzyme cost. The digested fragments were this separated using the agarose gel electrophoresis which showed continuous smear on the gel surface with the distribution of the difference fragment sizes being established. Digested pUC19 is a plasmid and able to transform itself on the transformation process where it can be able to multiply itself and express. Undigested pUC19 originate from E coli and contain high number of base pairs. The transformation efficiently portrayed shows that smaller pUC19 plasmid sin E choli can be manipulated and be transformed from the ampicilin forms. This shows that the DNA is in contact form with plasmid DNA being intact and with presence of viral chromosomes which can be transformed into high efficiencies. This transformation is through the resulting effect of digestion of peri plasmids. The undigested Puc19 shows presence base pairs which have the ability to perform recombination and be incorporated into cells, (Goto, Kenta & Yukio, 2013). The lanes which have recombination factor is able to facilitate the cloning of DNA in host cells.   This signifies recombination of various fragments of gel solution. The lanes that have been generated originated from digestion of particular DNA, which gives it equimolar amounts. Based on the lanes, there is variation on the number of non molar amounts, thus signifying that there is difference in band lengths. Others have shown to represent circular forms of the plasmids which is dependent on the age and quality of the plasmids. The existence of three forms of DNA formation which exists include linear formation, open circular formation and supercoiled forms. Plasmid DNA have been prevalently been studied in laboratory studies. After its preparation they exists in the three forms above. With good plasmid preparation, DNA often form plasmid which exist in any one strands of the DNA, this break causes the release of the phosphordiester backbones of the DNA to be released out. The visualising process of the agarose gel using the standard control tool is key to assess whether the bands have created a generation or not. Closer bands are well compressed than far away bands as indicated in the gel view. The standard marker used in this experiment was essential in ensuring that the standards sizes are generated using base pairs. This result signifies that electrophoresis is an effective way of separating nucleic acids. High gel agarose gives room for handling of low percentage gel separation. Due to the size of the base pair present in this experiment, has utilised field gel electrophoresis. This is   comparable to studies done (Lee et al, 2012), which have shown that sizes of DNA can be separated effectively through plotting on the log of molecular weight and different bands of DNA against the distance moved, this portray how different forms of gel can be able to move at different speeds. Super coiled plasmid DNA have sown to move faster, while those in linear formation travel averagely while open circular travel slowly. Goto, K., & Nagano, Y. (2013). Ultra-low background DNA cloning system. PloS one, 8(2), e56530. Kryndushkin DS, Alexandrov IM, Ter-Avanesyan MD & Kushnirov VV (2003). Yeast [PSI+]   prion aggregates are formed by small Sup35 polymers fragmented by Hsp10. Journal of Biological Chemistry.278 (49): 49636. Lee, P. Y., Costumbrado, J., Hsu, C. Y., & Kim, Y. H. (2012). Agarose gel electrophoresis for the separation of DNA fragments. Journal of visualized experiments: JoVE, (62). Sambrook J&Russel DW(2001). Molecular Cloning: A Laboratory Manual 3rd Ed. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, NY. Southern, E. M. (1975). Detection of specific sequences among DNA fragments separated by gel electrophoresis. J mol biol, 98(3), 503-517.

Thursday, February 13, 2020

Chronic Eczema Essay Example | Topics and Well Written Essays - 250 words

Chronic Eczema - Essay Example For instance, the methods of treating Chronic Eczema may change, hence rendering the previous routines useless. For example, a new method of diagnosing Chronic Eczema may be discovered, and hence taking of picture of the affected part by the patient and sending it to the Dermatologist becomes less useful. The technologies available to different patients are varied. The knowledge to make proper use of the technologies available to the patient are also not guaranteed. For instance, relying on the photos taken by the patient may not give a clear picture of the intensity of the infection, especially if the focus of the photos is not good. For this reason, relying on the patient’s technologies may impair the process of offering equitable health services. For equitability in health service delivery, practices such as diagnosis should be uniform across the patients. The virtual support hinders the patient from accessing quality services, which would be offered in the event of the patient visiting the GP and hospitals. It is likely that if the patient gets virtual support, he/ she doesn’t enjoy some of the services, which are difficult to implement in the online support

Saturday, February 1, 2020

Assignment Example | Topics and Well Written Essays - 500 words - 214

Assignment Example I believe that this is the sign that he was extremely talented. As the presented puts it, every next text that was writer afterward simply expanded the ides which were created in his two fundamental works. The first one is called The World as Will and Representation and the other one is called On the Fourfold Root of the Principle of Sufficient Reason. Another aspect of his life that really influenced me as the decision that he made when he was young. It is said that he could pursue many different careers, including running a business, but he knew that his accomplishments would lie in the academic field. Having learned about the idea which were develop by this philosopher, I must admit that he is truly one of the most wise scholars of his century and the science would have been greatly damaged in case Schopenhauer had chosen a different field of activity. It was suggested in the video that he was able to influence a considerable number of people who were later recognized as prominent individuals as well. It is quite remarkable to see the way he treated the concept of will and tried to use it in order to explain the world as it is. I believe that a careful examination of his legacy is beneficial to all

Friday, January 24, 2020

Cattells Big Five Factors Essay -- science

Cattell's Big Five Factors Cattell’s Big Five Factors of Personality, Behavioral Genetics, and Evolutionary Personality Theory. Current Research Raymond Cattell (1905-present) designed the â€Å"Big five Factors of Personality†, in which five classifications are revealed. Big Five factors: #1 extraversion vs. introversion, #2 agreeableness vs. antagonism, #3 conscientiousness vs. undirected ness, #4 neuroticism vs. emotional stability, and #5 openness to experience vs. not open to experience. Han’s Eysenck’s and Sir Francis Galton behavior genetics research and Arnold Buss’ three concerns for evolutionary personality theory coinsided with each other. The Big five represents a catalog of traits that some personality psychologists suggest capture the essence of individual differences in personality. Raymond Cattell used Allport and Odbert’s 4500 trait-descriptives in which he extracted 35 traits. After others continued to analyze these factors and found congruence with the ratings, that eventually became the Big five Factors of Personality. In order to fully understand the origin of these factors an outline for factor analysis must be explained. Factor analysis studies where conducted and the results where used in an analysis technique generally done with computers to determine meaningful relationships and patterns in behavioral data. Beginning with a large number of behavioral variables, the computer finds relationships or natural connections where variables are maximally correlated with one another and minimally correlated with other variables, and then it groups the data accordingly. After this process has been repeated many times a pattern of relationships or certain factors that capture the essence of all the data appears (Pervin & John 1999). The same process used to determine the Big Five Personality factors; copious amounts of different researchers that have done numerous tests and they all agree that the â€Å"Big five Factors† are the only consistently reliable factors that have been found. Big Five factors include: #1 extraversion vs. introversion, #2 agreeableness vs. antagonism, #3 conscientiousness vs. undirected ness, #4 neuroticism vs. emotional stability, and #5 openness to experience vs. not open to experience, these breakdown into understandable terms. #1 Extraversion implies an energetic approach to the social and material wo... ...between human nature and individual characteristics? He also acknowledged three criteria from evolutionary biology for determining a characteristic as a part of human nature. These are: it must be universal. Must be â€Å"innate, unconditioned, and relatively difficult to modify† (p.1139). And lastly it must have an adaptive function (Lindsey and Campbell p. 352,1998). In conclusion, all of these theories have laid the groundwork for mapping complex human behavior. It is still unclear when and how much of our personalities/traits come from genetics and how much is influenced by outside factors. Many believe you must learn of your past in order to succeed in the future, but understanding how we became what we are today is of equal importance. With the advances in technology, DNA/Genetics who knows what answers the future will hold for us. References Hall, C., Lindzey, G., Campbell, J. (1998). Theories of Personality (4th ed.) (pp.343-356) John Wiley and Sons, Inc. Pervin, L. & John, O. (Eds) (1999). Handbook of Personality: theory and research. New York: Gilford. Potkay, C. & Allen, B (1986). Personality: Theory, research, and applications. California: Brooks/Cole.

Thursday, January 16, 2020

Behind Closed Doors at WorldCom Essay

1.Two General Accounting employees—Dan Renfroe and Angela Walter—made journal entries in the amount of $150 million and $171 million, respectively, without detailed support. It was noted that this was not out of the ordinary at WorldCom. In your opinion, was this a proper accounting practice? Explain. Though this may not be out of the ordinary for WorldCom, this is not a correct accounting practice. The way the entries were made does not comply with the proper account practice according to GAAP. Detailed support is an important part of providing support to a journal entry and it explains the reason or purpose as to why the journal entry was created. 2.Based on GAPP, describe the propriety or impropriety of releasing of $150 million in line cost accruals in the Wireless division over Deloris DiCicco’s objections. Support your position using the authoritative accounting literature. When instructed to reduce the Wireless Division’s line cost by $150 million due to savings from the prior period, DiCicco refused because there was no support for the entry.   WorldCom would prepare an adjusting entry each month to recognize the estimated cost of the period as period expense, by capitalizing the expense as an accrued interest. According to GAAP, a line item cost must be reported as an expense on a company’s income statement. WorldCom capitalized the line expense, instead of expensing it and placed it on the balance sheet as an accrued liability rather than on the income statement as an operating expense. 3.On the topic of capitalizing line costs, critique the rationale included in CEO Scott Sullivan’s White Paper. Based on your own analysis of GAAP, explain the propriety or impropriety of capitalizing line costs in the telecom industry. In the White Paper presented to the Board of Directors, the CEO Scott Sullivan supported the decision to capitalize line costs. Sullivan provided that the White Paper was in line with the company’s goal of maintaining strong growth rate through increasing its capital investment. Management noted that the treatment of the E/R cots as an asset was in no way in any contradiction of the definition of an asset as per FASB Concept Statement No. 6 which states, â€Å"Assets are probable future economic benefits obtained or controlled by a particular entity as a result of past transactions or events†. However, as per GAAP, line costs must be reported as an expense in the company’s income statement as these are fundamentally,  ope rating expenses. It was put in the Balance Sheet as an accrued liability rather than in the income statement as an accrued expense. This resulted in falsely projecting income and profits; and concealing huge losses by wrongly capitalizing the line costs. 4.Consider journal entry that recognized $35 million of revenue in 2001 from the EDS contract based on WorlCom’s expectation that the five-year required cumulative minimum payment would not be met. Based on your own analysis of GAAP, explain the propriety to impropriety of this journal entry. This is not in compliance with the provisions of GAAP or SAB 101. Revenue should not be recognized until it is realized or becomes realizable and earned. If we followed this statement the company did not have realized revenue Furthermore, the penalty payments if enforced could not be paid till the year 2005 as stated in the contract. Also, the journal entry resulted in recognizing revenue when it was not earned or realized and thus, overstated the profits. 5.Why do you think the professionals in this case, most of whom are CPA’s, would agree to record a material journal entry contrary to their best professional judgment? I think that in many situations employees were able to twist statements which follow GAAP guidelines. May employees were convinced they were doing the right thing and those that were unwilling to participate were overlooked. Most of the material journal entries which were made contrary to best judgment were so done with a view to mask the declining profits and to show increasing profits, which in turn would increase stock prices. 6.In general, how does the role of Internal Auditing differ from the role of Independent (or External) Auditing? What is the role of Internal Auditing in a well-run corporation? When performed by internal auditors, what is a financial audit versus an operating audit? Do you think WorldCom’s Internal Audit Department was functioning as it should have been? Explain. Internal auditors work within an organization and report to its audit committee and/or directors. They help to design the company’s organizing systems and help develop specific risk management policies. External auditors are independent of the organization they are auditing. They report to the company’s shareholders. They provide their experienced opinion on the truthfulness of the company’s financial statements and perform work on a test basis to monitor systems in place. Internal Auditing  is designed to look at the key risks facing the business and how the business is managing those risks ef fectively. It usually results in recommendations for improvement across departments. Internal auditing is an independent, objective assurance and consulting activity designed to add value and improve an organization’s operations. It helps an organization accomplish its objectives by bringing a systematic, disciplined approach to evaluate and improve the effectiveness of risk management, control, and governance processes. A financial audit is an audit or examination of the financial reporting process, determining the reliability and integrity of the financial statements and preparation of such statements. It also involves an appraisal of the internal controls related to the finance function of the enterprise. An operational audit, on the other hand, is a systematic review and evaluation of an operational unit in terms of its effectiveness and efficiency of operations, accomplishment of its laid down objectives and goals, and determining its appropriateness in the use of various resources. It is clear that the WorldCom’s Internal Audit department was not functioning as it should have been. It was concentrating only on operational audits and totally avoiding financial audits. On the cause of cost-saving, it clearly avoided any and every function which could overlap with the role of the external auditors.

Tuesday, January 7, 2020

Overview of Noncount Nouns in English Grammar

A noncount noun is a  noun (such as oxygen, music, furniture, steam) that refers to something which cant be counted or divided. Also known as a mass noun. Contrast with count noun. With a few exceptions, noncount nouns take singular verbs and are used only in the singular. Many nouns have both countable and non-countable uses, such as the countable dozen eggs and the non-countable idiom egg on his face. Examples and Observations Arm in arm, the King and Bartholomew went down to the counting room to count out the gold. (Dr. Seuss,  The 500 Hats of Bartholomew Cubbins. Vanguard, 1938) Keep all trash and garbage away from your cat, and your cat out of trash cans and garbage bins. (Wendy Christensen, Outwitting Cats. Lyons Press, 2004) She considered, maybe for the first time, how lucky she was to be able to pick up the phone and call her mother whenever she needed some bad advice. (Brady Udall, The Lonely Polygamist. W.W. Norton, 2010) The novel manufactured to entertain great multitudes of people must be considered exactly like a cheap soap or a cheap perfume, or cheap furniture. (Willa Cather, The Novel Demeuble. The Editor, August 26, 1922) I read the news today, oh boy,about a lucky man who made the grade,and though the news was rather sad,well I just had to laugh. (John Lennon and Paul McCartney, A Day in the Life. Sgt. Peppers Lonely Hearts Club Band, 1967) Types of Noncount Nouns That May or May Not Take Determiners - Abstractions: democracy, education, health, knowledge, loveAn education is of utmost importance.Education is crucial to economic security.- Groups of things: clothing, equipment, garbage, homework, money, trafficThe homework for French class is time-consuming.I spend a lot of time doing homework.- Substances: air, blood, coffee, ice, rice, tea, water, woodThis tea is watery.She prefers tea for breakfast. (Cheryl Glenn and Loretta S. Gray, The Hodges Harbrace Handbook, 18th ed. Wadsworth, 2013)   [T]here is a resolute sadness between X and me that our marriage is over, a sadness that does not feel sad. (Richard Ford, The Sportswriter. Vintage, 1986)​ Noncount Nouns and Indefinite Articles Some noncount nouns accept the indefinite article when they are modified . . ., e.g.: They are doing a brisk business. (NOT * a business.)​ In some cases no modification seems to be required. In the following example, however, modification is in fact implied:​ She has had an education. [a good education] (Randolph Quirk et al., A Comprehensive Grammar of the English Language. Longman, 1985)   How do you go to a woman who lives at the foot of a mountain of sadness and shovel more around her ankles, the sadnesses of strangers? (Rick Bragg, All Over but the Shoutin. Random House, 1999) Quantifying Noncount Nouns What about a loaf of bread or a slice of bread? Arent these count nouns? The noncount noun, e.g. bread is still a noncount noun. What has happened is that we have added a quantifiying phrase, a loaf or a slice, before the noncount noun, bread.Many noncount nouns can be quantified, that is made countable, by adding certain phrases before them: a grain of sand, three bottles of water, a piece of advice. When one of these phrases comes before a noun, we call the entire group of words a noun phrase. (Andrea DeCapua, Grammar for Teachers: A Guide to American English for Native and Non-native Speakers. Springer, 2008) Noncount Nouns and Mass Nouns Non-count nouns are often called mass nouns. We have preferred non-count, in part because it reflects clearly the test we use for determining whether a noun is count or non-count, in part because mass is not suitable for the full range of non-count nouns. The term mass is readily applicable with nouns like water or coal that denote substances but it is less evident that it applies transparently to abstract non-count nouns such as knowledge, spelling, work. (Rodney Huddleston and Geoffrey Pullum, The Cambridge Grammar of the English Language. Cambridge University Press, 2002)